Research Chemical High Purity 99.0%Min.Thymosin Alpha 1 Thymalfasin 62304-98-7 Peptide Raw Powder with The Best Price
Product name
Thymosin alpha 1
CAS NO.
62304-98-7
Molecular formula
C129H215N33O55
Molecular weight
3108.3
Packing
Secured Disguised Package
Purity
99%
Appearance
White powder
Specification
1mg，2mg，5mg，10mg
Packing
Secured Disguised Package
Lead Time
7-14working days door to door
Introduction: Thymosin alpha 1(Ta1),a 28-amino acid peptide, was first described and characterized from calf thymuses in 1977. This peptide can enhance T-cell,dendritic cell(DC) and antibody responses, modulate cytokines and chemokines production and block steroid-induced apoptosis of thymocytes. Due to its pleiotropic biological activities, Ta1 has gained increasing interest in recent years and has been used for the treatment of various diseases in clinic. Accordingly, there is an increasing need for the production of this peptide.So far,Ta1 used in clinic is synthesized using solid phase peptide synthesis.Here,we summarize the genetic engineering methods to produce Ta1 using prokaryotic or eukaryotic expression systems.The effectiveness of these biological products in increasing the secretion of cytokines and in promoting lymphocyte proliferation were investigated in vitro studies.This opens the possibility for biotechnological production of Ta1 for the research and clinical applications. Research highlights Thymosin alpha 1(Ta1) has a lot of biological activities.Ta1 has a broad spectrum of applications in clinic. Genetic engineering expression of Ta1 has attracted more attention recently.Ta1 products obtained by genetic engineering may be applied in clinic in the future.
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